Why Blood Type May Matter for COVID Infection
WEDNESDAY, March 3, 2021 (HealthDay Information) — A brand new examine offers additional proof that folks with sure blood varieties could also be extra more likely to contract COVID-19.
The researchers centered on a protein on the floor of the SARS-CoV-2 virus known as the receptor binding area (RBD), which is the a part of the virus that attaches to the host cells. That makes it an necessary goal for scientists attempting to learn the way the virus infects individuals.
On this laboratory examine, the staff assessed how the SARS-CoV-2 RBD interacted with respiratory and purple blood cells in A, B and O blood varieties.
The outcomes confirmed that the SARS-CoV-2 RBD had a powerful desire for binding to blood group A discovered on respiratory cells, however had no desire for blood group A purple blood cells, or different blood teams discovered on respiratory or purple cells.
The SARS-CoV-2 RBD’s desire to acknowledge and fix to the blood kind A antigen discovered within the lungs of individuals with blood kind A could present perception into the potential hyperlink between blood group A and COVID-19 an infection, in keeping with the authors of the examine. It was revealed March 3 within the journal Blood Advances.
“It’s fascinating that the viral RBD solely actually prefers the kind of blood group A antigens which can be on respiratory cells, that are presumably how the virus is getting into most sufferers and infecting them,” mentioned examine creator Dr. Sean Stowell, from Brigham and Girls’s Hospital in Boston.
“Blood kind is a problem as a result of it’s inherited and never one thing we will change,” Stowell mentioned in a journal information launch. “But when we will higher perceive how the virus interacts with blood teams in individuals, we might be able to discover new medicines or strategies of prevention.”
These findings alone cannot absolutely describe or predict how coronaviruses would have an effect on sufferers of assorted blood varieties, the researchers famous.
“Our remark is just not the one mechanism accountable for what we’re seeing clinically, but it surely might clarify a number of the affect of blood kind on COVID-19 an infection,” Stowell and his staff mentioned.
The U.S. Facilities for Illness Management and Prevention has extra on COVID-19.
SOURCE: Blood Advances, information launch, March 3, 2021